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I can't confirm any issues with covering the Ford factory antenna on the roof with a solar panel, however the first roof rack I installed I did move the antenna outside of the solar panel where it was not covered only because I was preventatively doing it while I was at the installation point.
On my next build (Jon and Susan's Van) I did cover the antenna with a solar panel but I also installed a new stereo system with a separate GPS antenna mounted to the front windshield, it's difficult to say that the solar panel covering the antenna has affected the Ford sync systems GPS enough for it to not work (Jon and Susan are using Apple Car Play for navigation).
If you feel comfortable enough to relocate the Ford factory antenna it might be good to do this, seeing how Ford sometimes updates the system on the newer vans remotely.
If your van is a newer van, make a note that when you do relocate the antenna there is not that much black only about 8 in to work with so just consider the final mounting location on the roof when you're moving it, also you'll need to use a waterproof gland that allows for the wire to not be cut and instead be slipped over the wire to create the waterproof seal. let me know if you have any other questions on this I'll be happy to discuss further.
Original question by @jdierberger from https://youtu.be/I6c2vCiPhPM?si=VCpYL_FcpOSFxNGd